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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 11250
Species: Mus musculus
CRRD Object: Gene
Symbol: Rxra
Name: retinoid X receptor alpha
Acc ID: CHEBI:17336
Term: all-trans-retinol
Definition: A retinol in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:36106480464CTDVitamin A results in increased expression of RXRA mRNA

PMID:16180333
increases expressionISORGD:7369296480464CTDVitamin A results in increased expression of RXRA protein

PMID:17219422
multiple interactionsISORGD:7369296480464CTD[Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA

PMID:17244623
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.