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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 68393
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Kcnd2
Name: potassium voltage-gated channel subfamily D member 2
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in decreased expression of KCND2 mRNA

PMID:26496021
decreases expressionISORGD:685746480464CTDTestosterone results in decreased expression of KCND2 mRNA

PMID:21592394
multiple interactionsISORGD:685746480464CTD[Testosterone co-treated with Calcitriol] results in increased expression of KCND2 mRNA

PMID:21592394
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.