GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 61308
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Flt3
Name: fms-related tyrosine kinase 3
Acc ID: CHEBI:17356
Term: 2-acetamidofluorene
Definition: The parent of the class of 2-acetamidofluorenes, being an ortho-fused polycyclic arene that consists of 9H-fluorene bearing an acetamido substituent at position 2. It is a carcinogenic and mutagenic derivative of fluorene.
Chemical ID: MESH:D015073
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionEXP 6480464CTD2-Acetylaminofluorene affects the expression of FLT3 mRNA

PMID:18031378
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.