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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620872
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: F2rl3
Name: F2R like thrombin or trypsin receptor 3
Acc ID: CHEBI:17489
Term: 3',5'-cyclic AMP
Definition: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase.
Chemical ID: MESH:D000242
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7313946480464CTD[GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] inhibits the reaction [Colforsin results in increased chemical synthesis of Cyclic AMP], [GYPGKF-NH(2) binds to and results in increased activity of F2RL3 protein] which results in decreased chemical synthesis of Cyclic AMP

PMID:22207716
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.