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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 736871
Species: Homo sapiens
CRRD Object: Gene
Symbol: DHFR
Name: dihydrofolate reductase
Acc ID: CHEBI:17579
Term: beta-carotene
Definition: A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid.
Chemical ID: MESH:D019207
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:104716480464CTD[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA

PMID:24657404
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.