GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 631434
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Bbc3
Name: Bcl-2 binding component 3
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:15524846480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein modified form

SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein]

PMID:28675767
multiple interactionsISOCRRD:7353896480464CTD[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA

SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA]

PMID:24451382
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.