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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1312683
Species: Homo sapiens
CRRD Object: Gene
Symbol: EZH2
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Acc ID: CHEBI:17967
Term: urethane
Definition: A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages.
Chemical ID: MESH:D014520
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDUrethane results in increased expression of EZH2 mRNA

PMID:28818685
increases expressionISORGD:13126846480464CTDUrethane results in increased expression of EZH2 mRNA, Urethane results in increased expression of EZH2 protein

PMID:25168426
multiple interactionsISORGD:13126846480464CTDPhytic Acid inhibits the reaction [Urethane results in increased expression of EZH2 mRNA], Phytic Acid inhibits the reaction [Urethane results in increased expression of EZH2 protein]

PMID:25168426
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.