GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620047
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:18049
Term: piperidine
Definition: An azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine.
Chemical ID: MESH:C032727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISOCRRD:7308586480464CTDpiperidine analog results in decreased expression of IL2 mRNA

PMID:11859000
multiple interactionsISOCRRD:7333156480464CTDpiperidine inhibits the reaction [Cadmium Chloride results in decreased secretion of IL2 protein]

PMID:17706638
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.