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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2482
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cyp7a1
Name: cytochrome P450 family 7 subfamily A member 1
Acc ID: CHEBI:18291
Term: manganese atom
Definition: A manganese group element atom that has formula Mn.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityEXP 6480464CTDManganese results in increased activity of CYP7A1 protein

PMID:12700418
multiple interactionsEXP 6480464CTD[Manganese co-treated with Bilirubin] results in decreased activity of CYP7A1 protein

PMID:12700418
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.