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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 733581
Species: Homo sapiens
CRRD Object: Gene
Symbol: COX17
Name: cytochrome c oxidase copper chaperone COX17
Acc ID: CHEBI:18388
Term: apigenin
Definition: A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7. It induces autophagy in leukaemia cells.
Chemical ID: MESH:D047310
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:6205486480464CTDApigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of COX17 mRNA], Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of COX17 protein]

PMID:30107153
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.