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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1591925
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Golga4
Name: golgin A4
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13529476480464CTDNicotine results in increased expression of GOLGA4 mRNA

PMID:16949557
multiple interactionsISORGD:13529476480464CTDalpha-cobratoxin inhibits the reaction [Nicotine results in increased expression of GOLGA4 mRNA], Tubocurarine inhibits the reaction [Nicotine results in increased expression of GOLGA4 mRNA]

PMID:16949557
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.