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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1351608
Species: Homo sapiens
CRRD Object: Gene
Symbol: SPTBN1
Name: spectrin beta, non-erythrocytic 1
Acc ID: CHEBI:23924
Term: enzyme inhibitor
Definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Chemical ID: MESH:D004791
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SPTBN1 protein

PMID:23301498
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.