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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730881
Species: Homo sapiens
CRRD Object: Gene
Symbol: HRAS
Name: HRas proto-oncogene, GTPase
Acc ID: CHEBI:23924
Term: enzyme inhibitor
Definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Chemical ID: MESH:D004791
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] inhibits the reaction [HRAS protein binds to Guanosine Triphosphate], [Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] promotes the reaction [HRAS protein binds to Guanosine Diphosphate], Enzyme Inhibitors inhibits the reaction [SOS1 protein binds to [HRAS protein binds to Guanosine Diphosphate]]

PMID:25825487
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