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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1305379
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Clcn6
Name: chloride voltage-gated channel 6
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Clcn6increases expressionISORGD:13133736480464CTDAflatoxin B1 results in increased expression of CLCN6 mRNA

PMID:19770486
Clcn6increases methylationISORGD:13133726480464CTDAflatoxin B1 results in increased methylation of CLCN6 gene

PMID:27153756
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