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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621104
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Slc22a25
Name: solute carrier family 22, member 25
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a25affects expressionISORGD:13439506480464CTDAflatoxin B1 affects the expression of SLC22A9 protein

PMID:20106945
Slc22a25decreases expressionISORGD:13439506480464CTDAflatoxin B1 results in decreased expression of SLC22A9 mRNA

PMID:22100608, PMID:27153756
Slc22a25decreases methylationISORGD:13439506480464CTDAflatoxin B1 results in decreased methylation of SLC22A9 gene

PMID:27153756
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.