Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1593189
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gsta5
Name: glutathione S-transferase alpha 5
Acc ID: CHEBI:25195
Term: mercury atom
Definition: A zinc group element atom that has formula Hg.
Chemical ID: MESH:D008628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:16201186480464CTDMercury results in increased expression of GSTA1 mRNA

PMID:16243960, PMID:22579925
multiple interactionsISORGD:16201186480464CTDbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]], Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA], Dactinomycin inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA], Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of GSTA1 protein], Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of GSTA1 protein], Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA], Mercury promotes the reaction and results in increased expression of Tetrachlorodibenzodioxin promotes the reaction and results in increased expression of GSTA1 mRNA, Mercury results in increased expression of and results in increased activity of GSTA1 protein, NFE2L2 protein affects the reaction [Mercury results in increased expression of GSTA1 mRNA]

PMID:16243960, PMID:22579925
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.