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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1349145
Species: Homo sapiens
CRRD Object: Gene
Symbol: ITGB5
Name: integrin subunit beta 5
Acc ID: CHEBI:25434
Term: bis(2-chloroethyl) sulfide
Definition: An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention.
Chemical ID: MESH:D009151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:16176216480464CTDMustard Gas results in decreased expression of ITGB5 mRNA

PMID:16377760
multiple interactionsISORGD:16176216480464CTDDimercaprol inhibits the reaction [Mustard Gas results in decreased expression of ITGB5 mRNA]

PMID:16377760
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.