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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2059
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Adrb1
Name: adrenoceptor beta 1
Acc ID: CHEBI:2549
Term: albuterol
Definition: A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Chemical ID: MESH:D000420
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDAlbuterol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]

PMID:8096834
multiple interactionsISORGD:7312896480464CTDAlbuterol inhibits the reaction [cyanopindolol binds to ADRB1 protein], Albuterol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]

PMID:14730417, PMID:8096834
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.