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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730959
Species: Homo sapiens
CRRD Object: Gene
Symbol: SLC9A2
Name: solute carrier family 9 member A2
Acc ID: CHEBI:2639
Term: amiloride
Definition: A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid.
Chemical ID: MESH:D000584
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:37196480464CTD[Amiloride results in decreased activity of SLC9A2 protein] which results in decreased transport of Chlorides, [Amiloride results in decreased activity of SLC9A2 protein] which results in decreased transport of Sodium

PMID:10958346
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.