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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1306167
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Stub1
Name: STIP1 homology and U-box containing protein 1
Acc ID: CHEBI:26718
Term: solanesol
Definition: A nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer).
Chemical ID: MESH:C017719
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13146296480464CTD2-phenylacetylenesulfonamide inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]], geldanamycin inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]], N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2, 6-diamine inhibits the reaction [solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]], solanesol promotes the reaction [HSF1 protein binds to STUB1 protein]

PMID:25645596
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.