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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 14067695
Species: Sus scrofa
CRRD Object: Gene
Symbol: PRKACB
Name: protein kinase cAMP-activated catalytic subunit beta
Acc ID: CHEBI:2682
Term: amphotericin B
Definition: A macrolide antibiotic used to treat potentially life-threatening fungal infections.
Chemical ID: MESH:D000666
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRKACBincreases expressionEXP 6480464CTDAmphotericin B results in increased expression of PRKACG protein

PMID:24105867
PRKACBmultiple interactionsEXP 6480464CTDN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Amphotericin B results in increased expression of PRKACG protein]

PMID:24105867
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.