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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2612
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Fgfr4
Name: fibroblast growth factor receptor 4
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDCarbon Tetrachloride results in decreased expression of FGFR4 mRNA

PMID:16644059, PMID:17805973
increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of FGFR4 mRNA

PMID:17032414
decreases response to substanceISOCRRD:7366456480464CTDFGFR4 protein results in decreased susceptibility to Carbon Tetrachloride

PMID:12466116
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.