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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3374
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ppm1b
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1B
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDCarbon Tetrachloride results in decreased expression of PPM1B mRNA

PMID:30690589
increases methylationEXP 6480464CTDCarbon Tetrachloride results in increased methylation of PPM1B promoter

PMID:30690589
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