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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621238
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tnfrsf1b
Name: TNF receptor superfamily member 1B
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of TNFRSF1B protein

PMID:24389507
affects expressionISOCRRD:7315716480464CTDCarbon Tetrachloride affects the expression of TNFRSF1B mRNA

PMID:17484886
decreases response to substanceISOCRRD:7315716480464CTDTNFRSF1B gene mutant form results in decreased susceptibility to Carbon Tetrachloride

PMID:15760680
increases expressionISOCRRD:7315716480464CTDCarbon Tetrachloride results in increased expression of TNFRSF1B protein

PMID:29987408
multiple interactionsISOCRRD:7315716480464CTDPANX1 protein affects the reaction [Carbon Tetrachloride results in increased expression of TNFRSF1B protein]

PMID:29987408
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.