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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730938
Species: Homo sapiens
CRRD Object: Gene
Symbol: PRKN
Name: parkin RBR E3 ubiquitin protein ligase
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:617976480464CTDCarbon Tetrachloride results in decreased expression of PRKN protein

PMID:26882442
multiple interactionsISORGD:617976480464CTDMelatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRKN protein]

PMID:26882442
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.