GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3952
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:7309886480464CTDArsenic results in increased expression of VCAM1 protein

Arsenic results in increased expression of VCAM1 protein alternative form

PMID:17938729, PMID:23761297
multiple interactionsISOCRRD:7309886480464CTD[Arsenic results in increased expression of and results in increased secretion of MMP2 protein] which results in increased expression of VCAM1 protein

[Arsenic results in increased expression of and results in increased secretion of MMP9 protein] which results in increased expression of VCAM1 protein

PMID:26637202
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.