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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3001
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Lepr
Name: leptin receptor
Acc ID: CHEBI:2781
Term: apocynin
Definition: An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Chemical ID: MESH:C056165
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:108656480464CTDacetovanillone inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]

acetovanillone inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides]

PMID:19478208
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