Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3389
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Prkaca
Name: protein kinase cAMP-activated catalytic subunit alpha
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:13446086480464CTD[TNF protein co-treated with Resveratrol] results in increased expression of PRKACA protein

PRKACA protein affects the reaction [[TNF protein co-treated with Resveratrol] results in increased expression of SIRT1 protein]

PRKACA protein promotes the reaction [Resveratrol results in increased degradation of SQSTM1 protein]

PRKACA protein promotes the reaction [Resveratrol results in increased expression of SIRT1 protein]

PMID:24145604, PMID:25943029
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.