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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3845
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tf
Name: transferrin
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDresveratrol results in decreased expression of TF mRNA

PMID:19228061
affects secretionISORGD:13425936480464CTDresveratrol affects the secretion of TF protein

PMID:24802182
multiple interactionsISORGD:13425936480464CTDresveratrol inhibits the reaction [Lipopolysaccharides results in increased activity of TF protein]

PMID:16507316
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.