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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 737494
Species: Homo sapiens
CRRD Object: Gene
Symbol: SYP
Name: synaptophysin
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDresveratrol results in increased expression of SYP mRNA

PMID:18592012, PMID:21161674
multiple interactionsEXP 6480464CTDpyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of SYP mRNA]

PMID:21161674
multiple interactionsISORGD:113736480464CTDresveratrol inhibits the reaction [PPT1 gene mutant form results in decreased expression of SYP protein]

PMID:21224254
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.