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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621612
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nts
Name: neurotensin
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDCocaine results in increased expression of NTS mRNA

PMID:27899881
multiple interactionsEXP 6480464CTDNTS protein inhibits the reaction [Cocaine results in decreased secretion of gamma-Aminobutyric Acid]

PMID:18252810
increases expressionISORGD:13190936480464CTDCocaine results in increased expression of NTS mRNA

PMID:11120399
multiple interactionsISORGD:13190936480464CTDDRD3 protein affects the reaction [Cocaine results in increased expression of NTS mRNA]

PMID:11120399
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.