GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1308872
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Rbbp8
Name: RB binding protein 8, endonuclease
Acc ID: CHEBI:28088
Term: genistein
Definition: 7-Hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:13173546480464CTDGenistein results in increased expression of RBBP8 mRNA

PMID:15757668, PMID:23019147, PMID:26865667, PMID:26865669
increases expressionISOCRRD:16220916480464CTDGenistein results in increased expression of RBBP8 mRNA

PMID:21048042
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.