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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621254
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Fat1
Name: FAT atypical cadherin 1
Acc ID: CHEBI:28088
Term: genistein
Definition: 7-Hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDGenistein results in decreased expression of FAT1 mRNA

PMID:12075121
multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Genistein] results in increased methylation of FAT1 gene

PMID:28505145
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