Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1311155
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Il33
Name: interleukin 33
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il33decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of IL33 mRNA

PMID:18178546, PMID:20959002, PMID:21215274, PMID:32109520
Il33affects expressionISORGD:13224626480464CTDTetrachlorodibenzodioxin affects the expression of IL33 mRNA

PMID:21570461
Il33decreases expressionISORGD:13224626480464CTDTetrachlorodibenzodioxin results in decreased expression of IL33 mRNA

PMID:19933214
Il33increases expressionISORGD:13224616480464CTDTetrachlorodibenzodioxin results in increased expression of IL33 mRNA alternative form

PMID:31093659
Il33multiple interactionsISORGD:13224616480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL33 mRNA alternative form], Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to IL33 promoter]

PMID:31093659
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.