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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1323510
Species: Mus musculus
CRRD Object: Gene
Symbol: Akr1c21
Name: aldo-keto reductase family 1, member C21
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13539016480464CTDTetrachlorodibenzodioxin results in decreased expression of AKR1C2 mRNA

PMID:19619570
multiple interactionsISORGD:13539016480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AKR1C2 mRNA

PMID:19619570
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.