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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2954
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Kcnb1
Name: potassium voltage-gated channel subfamily B member 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7322116480464CTDTetrachlorodibenzodioxin affects the expression of KCNB1 mRNA

PMID:22298810
decreases expressionISORGD:7322116480464CTDTetrachlorodibenzodioxin results in decreased expression of KCNB1 mRNA

PMID:20106945, PMID:26159488
multiple interactionsISORGD:7322116480464CTDEndosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of KCNB1 mRNA]

PMID:26159488
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.