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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621063
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Csf1
Name: colony stimulating factor 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of CSF1 mRNA

PMID:22298810
affects expressionISOCRRD:7310676480464CTDTetrachlorodibenzodioxin affects the expression of CSF1 mRNA

PMID:21570461
decreases expressionISOCRRD:7310676480464CTDTetrachlorodibenzodioxin results in decreased expression of CSF1 mRNA

PMID:19770486, PMID:19933214
increases expressionISOCRRD:7310666480464CTDTetrachlorodibenzodioxin results in increased expression of CSF1 mRNA

PMID:19147701
multiple interactionsISOCRRD:7310666480464CTD3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CSF1 mRNA]

AG 1879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CSF1 mRNA]

AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CSF1 mRNA]

EGTA acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CSF1 mRNA]

methyl arachidonylfluorophosphonate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CSF1 mRNA]

PMID:19147701
multiple interactionsISOCRRD:7310676480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSF1 mRNA

PMID:17942748
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.