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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3112
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:28148
Term: sodium stibogluconate
Definition: A D-gluconate adduct of indefinite composition containing between 30 and 34% of antimony(V), calculated with reference to dried and methanol-free substance. It is used as a treatment for leishmaniasis.
Chemical ID: MESH:D000967
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1multiple interactionsISORGD:109196480464CTD[Lovastatin results in decreased activity of ABCC1 protein] which results in increased susceptibility to Antimony Sodium Gluconate

PMID:18056276
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