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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 620660
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ptpn6
Name: protein tyrosine phosphatase, non-receptor type 6
Acc ID: CHEBI:28148
Term: sodium stibogluconate
Definition: A D-gluconate adduct of indefinite composition containing between 30 and 34% of antimony(V), calculated with reference to dried and methanol-free substance. It is used as a treatment for leishmaniasis.
Chemical ID: MESH:D000967
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptpn6decreases activityISORGD:7341886480464CTDAntimony Sodium Gluconate results in decreased activity of PTPN6 protein

PMID:12399974
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.