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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1563070
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gpr137c
Name: G protein-coupled receptor 137C
Acc ID: CHEBI:28177
Term: theophylline
Definition: A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea.
Chemical ID: MESH:D013806
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpr137cincreases expressionISORGD:16032536480464CTDTheophylline results in increased expression of GPR137C mRNA

PMID:18951874
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.