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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69152
Species: Homo sapiens
CRRD Object: Gene
Symbol: EGFR
Name: epidermal growth factor receptor
Acc ID: CHEBI:28197
Term: daidzein
Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4'.
Chemical ID: MESH:C004742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA, [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR protein, [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA, [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR protein

PMID:19347870
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.