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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1307932
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cldn4
Name: claudin 4
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases abundanceISORGD:13174136480464CTDCLDN4 protein results in increased abundance of Copper

PMID:23053666
multiple interactionsISORGD:13174136480464CTD[CLDN4 protein results in increased abundance of Copper] promotes the reaction [[TYR protein results in increased oxidation of Levodopa] which results in increased chemical synthesis of Melanins], [CLDN4 protein results in increased expression of SLC31A1 protein] which results in increased import of and results in increased abundance of Copper

PMID:23053666
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.