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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2325527
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Mir133b
Name: microRNA 133b
Acc ID: CHEBI:28714
Term: S-butyl-DL-homocysteine (S,R)-sulfoximine
Definition: A sulfoximide that is the sulfoximine derivative of an analogue of DL-methionine in which the S-methyl group is replaced by S-butyl.
Chemical ID: MESH:D019328
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:16082346480464CTD[Buthionine Sulfoximine co-treated with Atorvastatin co-treated with Ciprofloxacin] results in increased expression of MIR133B mRNA, [Buthionine Sulfoximine co-treated with Lovastatin co-treated with Gemfibrozil] results in increased expression of MIR133B mRNA, [Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of MIR133B mRNA

PMID:28263783, PMID:29679711, PMID:30853469
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.