RGD Gene Chemical Interaction Report - Chinchilla Research Resource Database

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID:	1316138
Species:	Mus musculus
CRRD Object:	Gene
Symbol:	Lrrc57
Name:	leucine rich repeat containing 57

Acc ID:	CHEBI:28748
Term:	doxorubicin
Definition:	An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID:	MESH:D004317

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:1602825	6480464	CTD	Doxorubicin results in decreased expression of LRRC57 mRNA	PMID:29803840

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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