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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2012
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Acadm
Name: acyl-CoA dehydrogenase medium chain
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:100576480464CTDDoxorubicin results in decreased expression of ACADM mRNA, Doxorubicin results in decreased expression of ACADM protein

PMID:26873546
decreases expressionISORGD:7352596480464CTDDoxorubicin results in decreased expression of ACADM mRNA

PMID:29803840
multiple interactionsISORGD:100576480464CTD[Doxorubicin co-treated with Dexrazoxane] results in increased expression of ACADM mRNA

PMID:26873546
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