RGD Gene Chemical Interaction Report - Chinchilla Research Resource Database

GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID:	621883
Species:	Rattus norvegicus
CRRD Object:	Gene
Symbol:	Cnn1
Name:	calponin 1

Acc ID:	CHEBI:28748
Term:	doxorubicin
Definition:	An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID:	MESH:D004317

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO	RGD:731921	6480464	CTD	Doxorubicin affects the expression of CNN1 protein	PMID:29385562
increases expression	ISO	RGD:731921	6480464	CTD	Doxorubicin results in increased expression of CNN1 mRNA	PMID:29803840

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

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InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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