GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69651
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tgfbr2
Name: transforming growth factor, beta receptor 2
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISOCRRD:7343326480464CTDDoxorubicin affects the expression of TGFBR2 mRNA

PMID:29803840
multiple interactionsISOCRRD:7343336480464CTD[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of TGFBR2 mRNA

PMID:21040762
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.