GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1310844
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Dusp10
Name: dual specificity phosphatase 10
Acc ID: CHEBI:28783
Term: zinc protoporphyrin
Definition: A metalloprotoporphyrin that has formula C34H32N4O4Zn.
Chemical ID: MESH:C017803
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:13219796480464CTDzinc protoporphyrin inhibits the reaction [andrographolide results in increased expression of DUSP10 mRNA]

zinc protoporphyrin inhibits the reaction [andrographolide results in increased expression of DUSP10 protein]

PMID:29165873
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.