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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 68936
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Slc4a4
Name: solute carrier family 4 member 4
Acc ID: CHEBI:28787
Term: nitroglycerin
Definition: A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Chemical ID: MESH:D005996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDNitroglycerin results in increased expression of SLC4A4 mRNA

PMID:12102619
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.