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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2589
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: F9
Name: coagulation factor IX
Acc ID: CHEBI:28794
Term: coumarin
Definition: A chromenone having the keto group located at the 2-position.
Chemical ID: MESH:C030123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases response to substanceISORGD:7356206480464CTDF9 exon polymorphism results in increased susceptibility to coumarin, F9 protein mutant form results in increased susceptibility to coumarin

PMID:11307814
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.